Quinazoline, 4-chloro-6-methoxy-

Quinazoline, 4-chloro-6-methoxy- - Names and Identifiers

Name	4-Chloro-7-methoxyquinazoline
Synonyms	4-Chloro-7-methoxy-quizoline 4-Chloro-7-methoxyquinazoline 4-CHLORO-7-METHOXYQUINAZOLINE 4-chloro-6-methoxyquinazoline 4-CHLORO-6-METHOXY-QUINAZOLINE Quinazoline, 4-chloro-6-methoxy- Quinazoline, 4-chloro-7-methoxy-
CAS	55496-52-1
InChI	InChI=1/C9H7ClN2O/c1-13-6-2-3-7-8(4-6)11-5-12-9(7)10/h2-5H,1H3

Quinazoline, 4-chloro-6-methoxy- - Physico-chemical Properties

Molecular Formula	C9H7ClN2O
Molar Mass	194.62
Density	1.333±0.06 g/cm3(Predicted)
Boling Point	323.0±22.0 °C(Predicted)
Flash Point	149.1°C
Vapor Presure	0.000509mmHg at 25°C
pKa	1.00±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.628

Quinazoline, 4-chloro-6-methoxy- - Introduction

It is an organic compound whose chemical formula is C10H7ClN2O. The following is a description of its nature, use, preparation and safety information:

Nature:
is a solid with a white to yellowish crystalline appearance. It has moderate solubility and is soluble in many organic solvents, such as ethanol, dimethylformamide and dichloromethane. This compound is stable at normal temperature, but may decompose at high temperature.

Use:
It is often used as an intermediate in organic synthesis. It can be used in the synthesis of drugs, chemical reagents and pesticides and other organic compounds. The compound can be used as a starting material for drug research, helping to discover new active drug molecules.

Preparation Method:
Synthesize can be obtained by reacting 2-amino -4-chloranil with methanol. The specific synthesis steps may be as follows: firstly, 2-amino-4-chloranil is reacted with sulfurous acid by heating, and then esterified with methanol to finally obtain the target product.

Safety Information:
General laboratory safety practices should be followed when handling the phosphor. The compound is irritating to the skin and eyes and contact should be avoided. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during operation. At the same time, it should be operated in a well-ventilated place to avoid inhaling its dust or steam. If exposed or inhaled, rinse immediately and seek medical help.

Last Update：2024-04-09 21:11:58